Life's Roller Coaster

If I'm missing, or not taking messages sorry – I'm more angry about letting my friends down than YOU will ever be at being let down! Unfortunately that is sometimes a side effect of Cancer! Mea Culpa: may I blame being short fused & grumpy on it too! My first symptoms presented in Nov-1998 – Follow The Trail on >DIARY of CANCER< Immediately Below!

Gene-Altering Treatments for #Cancer …

DO MAKE USE of LINKS,
>SEARCH<
&
>Side Bars<
&
The Top Bar >PAGES<

~~~~~~~~~~#########~~~~~~~~~~

.

Gene-Altering Treatments for #Cancer …

.
~~~~~~~~~~#########~~~~~~~~~~

Posted by:
Greg Lance – Watkins
Greg_L-W

eMail:
Greg_L-W@BTconnect.com

The BLOG:
https://InfoWebSiteUK.wordpress.com

The Main Web Site:
www.InfoWebSite.UK

~~~~~~~~~~#########~~~~~~~~~~

 .

Hi,

Cells taken from cancer patients are genetically engineered to fight cancer at a Kite processing facility. Credit Kite Pharma

The Food and Drug Administration on Wednesday approved the second in a radically new class of treatments that genetically reboot a patient’s own immune cells to kill cancer.

The new therapy, Yescarta, made by Kite Pharma, was approved for adults with aggressive forms of a blood cancer, non-Hodgkin’s lymphoma, who have undergone two regimens of chemotherapy that failed.

The treatment, considered a form of gene therapy, transforms the patient’s cells into what researchers call a “living drug” that attacks cancer cells. It is part of the rapidly growing field of immunotherapy, which uses drugs or genetic tinkering to turbocharge the immune system to fight disease. In some cases the treatments have led to long remissions.

“The results are pretty remarkable,” said Dr. Frederick L. Locke, a specialist in blood cancers at the Moffitt Cancer Center in Tampa, and a leader of a study of the new treatment. “We’re excited. We think there are many patients who may need this therapy.”

He added, “These patients don’t have other options.”

About 3,500 people a year in the United States may be candidates for Yescarta. It is meant to be given once, infused into a vein, and must be manufactured individually for each patient. The cost will be $373,000.

Continue reading the main story

 

The treatment was originally developed at the National Cancer Institute, by a team Dr. Steven Rosenberg led. The institute entered an agreement with Kite in 2012, in which the company helped pay for research and received rights to commercialize the results.

Largely on the strength of the new drug and related research, the drug giant Gilead purchased Kite in August, for $11.9 billion.

“Today marks another milestone in the development of a whole new scientific paradigm for the treatment of serious diseases,” the F.D.A. commissioner, Dr. Scott Gottlieb, said in a statement. “In just several decades, gene therapy has gone from being a promising concept to a practical solution to deadly and largely untreatable forms of cancer.”

Side-effects can be life-threatening, however. They include high fevers, crashing blood pressure, lung congestion and neurological problems.In some cases, patients have required treatment in an intensive care unit. In the study that led to the approval, two patients died from side effects. Doctors have learned to manage them better, but it takes training and experience.

Partly for that reason, Yescarta, like Kymriah, will be introduced gradually, and will be available only at centers where doctors and nurses have been trained in using it.

“Ten to 15 authorized institutions will be ready to go at the time of the launch,” a spokeswoman for Kite, Christine Cassiano, said. “In 12 months, we expect to have 70 to 90. There’s a lot that goes into it, making sure each institution is ready to go.”

Companies have been racing to develop new forms of immunotherapy. The first cell-based cancer treatment — Kymriah, made by Novartis — was approved in August for children and young adults with an aggressive type of acute leukemia. It will cost $475,000, but the company has said it will not charge patients who do not respond within the first month after treatment. Novartis is expected to ask the F.D.A. to approve Kymriah for lymphoma and other blood cancers as well, and may vary its price depending on how well it works for those diseases.

Kite also plans to seek approval for other blood cancers, but does not plan to vary Yescarta’s price, said Ms. Cassiano.

The company also hopes that Yescarta will eventually be approved for earlier stages of lymphoma, rather than being limited to patients with advanced disease who have been debilitated by multiple types of chemotherapy that did not work, said Dr. David D. Chang, Kite’s chief medical officer and executive vice president for research and development.

“This is the beginning of many developments in cell therapy in the next few years,” Dr. Chang said in an interview.

 

He said the F.D.A. had “embraced” the concept of cell therapy, designating it a breakthrough and accelerating the approval process to speed its availability to cancer patients, many of whom do not have time to wait.

Kite and Novartis also hope to produce cell therapies for so-called solid tumors — like those of the lung, prostate, breast and colon — which account for about 90 percent of all deaths from cancer.

Before it was approved and named Yescarta, Kite’s treatment was known by other names: axi-cel, axicabtagene ciloleucel, or KTE-C19.

The study that led to approval enrolled 111 patients at 22 hospitals; 101 of them received Yescarta. They had one of three diseases: diffuse large B-cell lymphoma, primary mediastinal B-cell lymphoma or transformed follicular lymphoma.

Initially, 54 percent had complete remissions, meaning that their tumors disappeared. Another 28 percent had partial remissions, in which tumors shrank or appeared less active on scans. After six months, 80 percent of the 101 were still alive.

With a median follow-up of 8.7 months, 39 percent of the 101 were still in complete remission — a much higher rate than achieved with earlier treatments — and 5 percent still had partial remissions.

“Many patients were seriously contemplating their own mortality,” said Dr. Caron A. Jacobson, who helped conduct the study at the Dana-Farber Cancer Institute and Brigham and Women’s Cancer Center in Boston. “We would be talking to them about other clinical trials, but also about hospice care and quality of life and comfort. You’re really seeing people get their life back. After a couple weeks in the hospital and a couple weeks at home, they go back to work. On its face, it’s quite remarkable and revolutionary.”

The treatment requires removing millions of a patient’s T-cells — a type of white blood cell that is critical to the immune system — freezing them and shipping them to Kite to be genetically engineered to kill cancer cells. The process reprograms the T-cells to attack B-cells, normal parts of the immune system that turn malignant in certain blood cancers. The revved-up T-cells — now known as “CAR-T cells” — are then frozen again and shipped back to the hospital to be dripped into the patient. The turnaround time is about 17 days.

Kite’s cell-processing facility, in El Segundo, Calif., can provide the treatment for 4,000 to 5,000 patients a year, Ms. Cassiano said, adding that the company has applied for approval in Europe, and if it is granted, will probably build a plant there.

Tina Bureau, a fifth-grade teacher from Queensbury, N.Y., was one of the lymphoma patients in the study. Previously, she’d had several types of chemotherapy.

“The cancer would shrink but then it would come right back,” she said.

Last spring, she had the T-cell treatment at the Dana-Farber Cancer Institute and Brigham and Women’s Hospital in Boston. The side effects were ferocious.

“You don’t even recognize your family members,” Ms. Bureau said. “I had some bleeding on my brain, and had to be put in intensive care. The week it was happening, I don’t remember a lot. It was much more difficult for my family than me.”

Within a month, she had a complete remission, which has continued. She is back at work, full time.

“Yes, it can pose life threatening problems,” Ms. Bureau said. “But when you’re in a situation where your life’s threatened anyway, I don’t feel you have anything to lose.”

To see the original of this article CLICK HERE
.
Regards,
     Greg_L-W
Greg Lance-Watkins
.
 Please Be Sure To
& Link to my My Blogs
To Spread The Facts World Wide To Give Others HOPE
I Have Been Fighting Cancer since 1997 & I’M STILL HERE!
I Have Cancer, Cancer Does NOT Have Me
I just want to say sorry for copping out at times and leaving my wife Lee and friends to cope!
Any help and support YOU can give her will be hugely welcome.
I do make a lousy patient!

.

If YOU want to follow my fight against Cancer from when it started and I first presented with symptoms in 1998 see The TAB at the Header of this Blog. called >DIARY of Cancer ….ARCHIVEMEDICAL LINKSCANCER LINKSHOT LINKS< in the Sidebar.
.
YOU are welcome to call me, minded that I am NOT medically trained, if you believe I can help you in ANY way. .

Regards,
Greg_L-W.

~~~~~~~~~~#########~~~~~~~~~~
.
Posted by: Greg Lance-Watkins
tel: 44 (0)1594 – 528 337
Calls from ‘Number Withheld’ phones Are Blocked

All unanswered messages are recorded.
Leave your name & a UK land line number & I will return your call.

‘e’Mail Address: Greg_L-W@BTconnect.com

Skype: GregL-W

TWITTER: @Greg_LW

DO MAKE USE of LINKS,
>SEARCH<
&
>Side Bars<
&
The Top Bar >PAGES<
I try to make every effort to NOT infringe copyrights in any commercial way & make all corrections of fact brought to my attention by an identifiable individual
.

Please Be Sure To
.Follow Greg_LW on Twitter.

Re-TWEET my Twitterings
https://twitter.com/Greg_LW

& Publicise

My MainWebSite & Blogs

To Spread The Facts World Wide


eMail:
Greg_L-W@BTconnect.com

The BLOG:
https://InfoWebSiteUK.wordpress.com

The Main Web Site:
www.InfoWebSite.UK

~~~~~~~~~~#########~~~~~~~~~~

Enhanced by Zemanta
Advertisements

How to Create a Peaceful At-Home Hospice for Your Loved One …

DO MAKE USE of LINKS,
>SEARCH<
&
>Side Bars<
&
The Top Bar >PAGES<

~~~~~~~~~~#########~~~~~~~~~~

.

How to Create a Peaceful At-Home Hospice for Your Loved One …

.
~~~~~~~~~~#########~~~~~~~~~~

Posted by:
Greg Lance – Watkins
Greg_L-W

eMail:
Greg_L-W@BTconnect.com

The BLOG:
https://InfoWebSiteUK.wordpress.com

The Main Web Site:
www.InfoWebSite.UK

~~~~~~~~~~#########~~~~~~~~~~

 .

Hi,

.

How to Create a Peaceful At-Home Hospice for Your Loved One

by HomeAdvisor

Elderly woman in wheelchair.

Given the option of spending the end of your life in a hospital versus in your own home, what would you choose? For most of us, the answer is simple, especially for those with a spouse or family. We would much prefer to live out our days and die peacefully in the comfort and privacy of our own home, surrounded by memories and the people we love.

Unfortunately, the decision is not always up to us. The type of treatment or end-of-life care we need will determine whether spending our final days, weeks, or months at home is an option.

Those who require medical intervention like IV pain medication or frequent procedures like X-rays may not be candidates for at-home care. However, many end-of-life patients receiving palliative care to keep them comfortable and pain-free can receive that same care from an in-home nurse or family member. In the end, this option can be less costly and more fulfilling. One study suggests people who spend their final days at home live longer and enjoy a better quality of life.

If your partner or loved one prefers to pass away at home, the existing space will likely require special attention. From structural modifications to allow for special equipment to finding ways for your loved one to maintain independence, this guide will help you create a suitable place to spend life’s final, precious moments, and to pass away peacefully.

Step 1: Creating a Soothing Space

Start with a good cleaning
For many people in poor health, basic tasks such as dusting and vacuuming are difficult. As a result, their homes can become dirty and in disrepair. Do a walk-through of the home. Make a list of any repairs that need to be made. Be especially vigilant about problems like water damage, which can lead to mold growth and cause respiratory issues. If you can’t take care of the to-dos yourself, enlist a family member or professional cleaning service to help.

Change as little as possible
Aside from providing a clean environment free from health hazards, you should leave as much as you can unaltered. There is comfort in the familiar, so it’s important to keep things as close as you are able to the home your loved one knows and loves.

  • Leave photographs and artwork on the walls These and table-top knickknacks and trinkets bring a sense of normalcy to a person as they cope with end-of-life issues.
  • Keep books and other hobbies close at hand, since these activities can reduce stress.
  • keep their pet in the home if at all possible. A cat or dog is both a friend and welcome distraction. Although your loved one may not be able to care for a pet on his or her own, the comfort their friend brings may be worth the effort. If taking care of the pet is too much strain on the caregiver(s), consider hiring a service.

Rearrange if necessary
In the case of bedridden patients who have little access to the rest of the home, it may make sense to rearrange the room where they spend most of their time to include more of their favorite possessions. Ask your loved one what items bring them joy, and make room for those belongings. With their permission, you can place photos from throughout the home into photo books and compile other beloved items in a basket to be kept within arm’s reach. Or, if they want to be in a more central location, move the bed to the living room or dining area so they are not isolated. This may also help visitors feel more comfortable.

Step 2: Accommodating Special Equipment

In addition to minor repairs and rearranging, you will need to ensure the home is ready for special equipment, like wheelchairs and walkers. This includes removing slippery rugs and making a clear path between furniture with plenty of clearance. In the event you need to make structural changes, like widening doorways or adding ramps, consult a professional contractor to ensure it is done safely and according to code.

Small changes that will make the home safer and easier to navigate may include:

  • Swapping door knobs for levers – This may help arthritic patients maintain a better grip.
  • Adapting existing furniture pieces – Add foam risers to make getting in and out of seats easier.
  • Adding ample lighting – This is especially important for those with poor eyesight. Consider adding floor lamps and replacing bulbs in existing fixtures with something brighter.
  • Addressing outdoor spaces – A safe place to get some fresh air can drastically improve quality of life.

Elderly individual receiving care outdoors

Step 3: Maintaining Their Independence

Being able to perform some everyday activities independently, however small, may help in maintaining a sense of dignity. If you can, ensure your loved one has shoes and clothes they can slip on and off by themselves. Let them look through their own mail, give them their own TV remote, and let them spend some time alone. Even if a caregiver is just in the next room, it is imperative your loved one has some time to themselves to rest, think, and cope.

  • Plan their meals in advance – The kitchen is one of the easiest places in the house for a patient to injure him or herself. To help avoid this, prep meals and snacks ahead of time or purchase them ready-made. Keep them on hand and, if they require heating, make sure it can be done in a microwave and provide instructions. In some cases, hospice will provide a separate caregiver to do light cooking and cleaning. You can also look into meal-delivery services like Meals on Wheels.
  • Maintain their sense of privacy – This is another big concern, especially when it comes to personal care issues like bathing and using the restroom. While the patient will more than likely require some assistance, you can promote independence in the bathroom with modifications like grab bars, tub benches, and raised commode seats. If a bedside toilet is necessary, position it behind curtains or a movable screen.
  • Keep some your own peace of mind – Depending on the level of the patient’s independence, family members may want to consider a medical alert system that will allow the patient to notify someone in the event of a fall or other emergency. If your loved one will be alone at any point of the day or night, this can bring him or her (as well as family members and caregivers) peace of mind.

Step 4: Making Room for Full-Time Care

When preparing a space for the end of a life, the dying party is not the only person to consider. You must ensure the caregivers, usually several family members and/or nurses, are comfortable and cared for as well. Whether they live in the home full time or work shifts, caregivers will need a space of their own to place their belongings and regroup after the physically- and emotionally-stressful moments caring for a dying patient or family member will inevitably bring.

  • Give them their own space – If you don’t have a spare bedroom, a corner of the kitchen or family room will work, as long as it’s designated for the individual specifically.
  • Help them stay connected – You may also want to invest in services like WiFi. Even if your loved one doesn’t have a computer or smartphone, most people today need to be connected.
  • Make sure there is ample parking and food for each caregiver. – Many of us are at our worst behind the wheel or hungry. Providing these things for the caregiver may go a long way toward keeping them in positive spirits at a difficult time.

While none of these items are necessities, it will help the person caring for your loved one enjoy his or her time there, in turn helping him or her take better care of the patient. After all, that’s what it’s all about: caring for your loved one and treating him or her as you would want to be treated. As long as we show kindness and compassion to our loved ones throughout the process, they will be able to say goodbye with the dignity they deserve.

To see the original of this article CLICK HERE
.
Regards,
     Greg_L-W
Greg Lance-Watkins
.
 Please Be Sure To
& Link to my My Blogs
To Spread The Facts World Wide To Give Others HOPE
I Have Been Fighting Cancer since 1997 & I’M STILL HERE!
I Have Cancer, Cancer Does NOT Have Me
I just want to say sorry for copping out at times and leaving my wife Lee and friends to cope!
Any help and support YOU can give her will be hugely welcome.
I do make a lousy patient!

.

If YOU want to follow my fight against Cancer from when it started and I first presented with symptoms in 1998 see The TAB at the Header of this Blog. called >DIARY of Cancer ….ARCHIVEMEDICAL LINKSCANCER LINKSHOT LINKS< in the Sidebar.
.
YOU are welcome to call me, minded that I am NOT medically trained, if you believe I can help you in ANY way. .

Regards,
Greg_L-W.

~~~~~~~~~~#########~~~~~~~~~~
.
Posted by: Greg Lance-Watkins
tel: 44 (0)1594 – 528 337
Calls from ‘Number Withheld’ phones Are Blocked

All unanswered messages are recorded.
Leave your name & a UK land line number & I will return your call.

‘e’Mail Address: Greg_L-W@BTconnect.com

Skype: GregL-W

TWITTER: @Greg_LW

DO MAKE USE of LINKS,
>SEARCH<
&
>Side Bars<
&
The Top Bar >PAGES<
I try to make every effort to NOT infringe copyrights in any commercial way & make all corrections of fact brought to my attention by an identifiable individual
.

Please Be Sure To
.Follow Greg_LW on Twitter.

Re-TWEET my Twitterings
https://twitter.com/Greg_LW

& Publicise

My MainWebSite & Blogs

To Spread The Facts World Wide


eMail:
Greg_L-W@BTconnect.com

The BLOG:
https://InfoWebSiteUK.wordpress.com

The Main Web Site:
www.InfoWebSite.UK

~~~~~~~~~~#########~~~~~~~~~~

Enhanced by Zemanta

New heart attack blood test could save NHS millions …

DO MAKE USE of LINKS,
>SEARCH<
&
>Side Bars<
&
The Top Bar >PAGES<

~~~~~~~~~~#########~~~~~~~~~~

.

New heart attack blood test could save NHS millions …

.
~~~~~~~~~~#########~~~~~~~~~~

Posted by:
Greg Lance – Watkins
Greg_L-W

eMail:
Greg_L-W@BTconnect.com

The BLOG:
https://InfoWebSiteUK.wordpress.com

The Main Web Site:
www.InfoWebSite.UK

~~~~~~~~~~#########~~~~~~~~~~

 .

Hi,

New heart attack blood test could save NHS millions

St Thomas’ hospital in London, which undertakes 7,800 heart attack tests a year, would be in line to save £800,000 alone.

More than two-thirds of people who go to A&E with chest pains have not had a heart attack
Image: More than two-thirds of people who go to A&E with chest pains have not had a heart attack

A blood test that speeds up the diagnosis of heart attacks could save the NHS millions of pounds every year, according to new research.

The new test is much more accurate than the one currently used and could free up doctors’ time and NHS beds.

 

More than two-thirds of people who go to A&E with chest pains have not suffered a heart attack.

But all of those patients undergo a blood test when they arrive and again three hours later to try and detect damage to the heart muscle.

The current test works by analysing biomarkers – including cardiac troponin. Those with undetectable levels of cardiac troponin are classified as low risk and are discharged from hospital.

But up to 85% of all patients fall into an intermediate risk group and require an overnight stay and further blood tests.

Scientists from King’s College London have developed a new test which looks at another biomarker – cardiac myosin-binding protein C (cMyC) – which is more sensitive to damage in the heart muscle.

Levels of cMyC in the blood increase rapidly after a heart attack – to a higher extent than troponin.

The new test – which could be rolled out across the NHS in the next five years – can detect a heart attack much more rapidly and could see those not suffering a heart attack sent home sooner.

The study, on more than 2,000 people in Switzerland, Italy and Spain, was funded by the British Heart Foundation (BHF) and published in the journal Circulation.

It found that the new test doubled the number of patients diagnosed as not having a heart attack.

Experts worked out that just one UK hospital – St Thomas’ in London which carries out 7,800 heart attack tests each year – could save £800,000 a year in reduced admissions and freed up beds.

Dr Tom Kaier, one of the lead researchers, said: “We often see patients in hospital who have to stay for further tests as a result of a mildly abnormal blood test – this is stressful and often unnecessary.

“Our research shows that the new test has the potential to reassure many thousands more patients with a single test, improving their experience and freeing up valuable hospital beds in A&E departments and wards across the country.”

To see the original of this article CLICK HERE

‘Instant’ blood test for heart attacks

  • 27 September 2017

A blood test that could rule out a heart attack in under 20 minutes should be used routinely, say UK researchers.

A team from King’s College London have tested it on patients and say the cMyC test could be rolled out on the NHS within five years.

They claim it would save the health service millions of pounds each year by freeing up beds and sending well patients home.

About two-thirds of patients with chest pain will not have had a heart attack.

A heart trace, called an ECG, can quickly show up major heart attacks, but it is not very good at excluding more common, smaller ones that can still be life-threatening.

Currently, patients with suspect chest pain and a clear ECG can have a different heart-attack blood test, called troponin, when they arrive at A&E. But it needs to be repeated three hours later to pick up signs of heart muscle damage.

Alison Fullingham, 49 and from Bolton, did not realise she was having a heart attack when she experienced pain in her upper chest, neck and jaw.

Despite a small change in her ECG, doctors initially suspected she was having a simple panic attack.

It was only hours later when her troponin tests came back that the correct diagnosis was reached.

Rapid diagnosis

Levels of cMyC (cardiac myosin-binding protein C) in the blood rise more rapidly and to a higher extent after a heart attack than troponin proteins, studies suggest.

That means doctors can use the new test to rule out a heart attack in a higher proportion of patients straightaway, according to the researchers who report their trial findings in the journal Circulation.

They carried out troponin and cMyC blood tests on nearly 2,000 people admitted to hospitals in Switzerland, Italy and Spain with acute chest pain.

The new test was better at giving patients the all-clear within the first three hours of presenting with chest pain.

Dr Tom Kaier, one of the lead researchers, funded by the British Heart Foundation (BHF) at St Thomas’ Hospital, London, said: “Our research shows that the new test has the potential to reassure many thousands more patients with a single test, improving their experience and freeing up valuable hospital beds in A&E departments and wards across the country.”

He says if the test were to be used routinely, it could provide doctors with reliable results within 15 to 30 minutes. It is only being used for research at the moment, however.

Dr Kaier’s hospital carries out around 7,800 troponin blood tests each year. By his calculations, switching to cMyC would save his hospital £800,000 through reduced admissions. Extrapolate that to other NHS hospitals and the savings could be millions of pounds, he says.

Prof Simon Ray, from the British Cardiovascular Society, said more research was needed before the new test could replace the troponin test.

“Unlike currently available blood tests which need to be repeated at least three hours after pain it looks as though a single test is enough to make a confident decision on whether a patient has or has not suffered a heart attack. Not only can it be done earlier after the onset of symptoms but it also seems to be better at discriminating between heart attacks and other causes of chest pains. This is very important.”

To view the Original Article CLICK HERE

.
Regards,
     Greg_L-W
Greg Lance-Watkins
.
 Please Be Sure To
& Link to my My Blogs
To Spread The Facts World Wide To Give Others HOPE
I Have Been Fighting Cancer since 1997 & I’M STILL HERE!
I Have Cancer, Cancer Does NOT Have Me
I just want to say sorry for copping out at times and leaving my wife Lee and friends to cope!
Any help and support YOU can give her will be hugely welcome.
I do make a lousy patient!

.

If YOU want to follow my fight against Cancer from when it started and I first presented with symptoms in 1998 see The TAB at the Header of this Blog. called >DIARY of Cancer ….ARCHIVEMEDICAL LINKSCANCER LINKSHOT LINKS< in the Sidebar.
.
YOU are welcome to call me, minded that I am NOT medically trained, if you believe I can help you in ANY way. .

Regards,
Greg_L-W.

~~~~~~~~~~#########~~~~~~~~~~
.
Posted by: Greg Lance-Watkins
tel: 44 (0)1594 – 528 337
Calls from ‘Number Withheld’ phones Are Blocked

All unanswered messages are recorded.
Leave your name & a UK land line number & I will return your call.

‘e’Mail Address: Greg_L-W@BTconnect.com

Skype: GregL-W

TWITTER: @Greg_LW

DO MAKE USE of LINKS,
>SEARCH<
&
>Side Bars<
&
The Top Bar >PAGES<
I try to make every effort to NOT infringe copyrights in any commercial way & make all corrections of fact brought to my attention by an identifiable individual
.

Please Be Sure To
.Follow Greg_LW on Twitter.

Re-TWEET my Twitterings
https://twitter.com/Greg_LW

& Publicise

My MainWebSite & Blogs

To Spread The Facts World Wide


eMail:
Greg_L-W@BTconnect.com

The BLOG:
https://InfoWebSiteUK.wordpress.com

The Main Web Site:
www.InfoWebSite.UK

~~~~~~~~~~#########~~~~~~~~~~

Enhanced by Zemanta

IN MEMORIAM – A Tribute To David Tang 02-Aug-1954 > 30-Aug-2017, from within the fashion industry …

DO MAKE USE of LINKS,
>SEARCH<
&
>Side Bars<
&
The Top Bar >PAGES<

~~~~~~~~~~#########~~~~~~~~~~

.

IN MEMORIAM – A Tribute To David Tang 02-Aug-1954 > 30-Aug-2017, from within the fashion industry …

.
~~~~~~~~~~#########~~~~~~~~~~

Posted by:
Greg Lance – Watkins
Greg_L-W

eMail:
Greg_L-W@BTconnect.com

The BLOG:
https://InfoWebSiteUK.wordpress.com

The Main Web Site:
www.InfoWebSite.UK

~~~~~~~~~~#########~~~~~~~~~~

 .

Hi,

having so recently posted David Tang’s praise of the NHS on 07-Aug-2017 it was sad to read of his demise.

If you missed my earlier article CLICK HERE

A Tribute To David Tang

Emma Weymouth pays tribute to her close friend and Shanghai Tang founder David Tang: a brilliant man who was loved so much and will be missed by so many


THERE are no words to do justice to David Tang, and as I write I can imagine him scoffing, correcting my grammar and blasting me with a one-liner to well and truly put me in my place. Always keeping us on our toes, one step ahead and ready at the drop of a hat to say something shocking at the top of his booming voice, outrageous enough to reduce a room full of his esteemed guests to a quivering mass of raucous laughter. Among countless other attributes, we loved him for his ruthless sense of humour – if you told him you’d lost 10 pounds, he would look you calmly in the eye and say, “What, sterling?” then chuckle with his familiar grin and happy snort. He was certainly the funniest, most intelligent and supremely generous friend any of us will ever have.

The inimitable David Tang

Getty Images

This week we lost one of the greats. A wit like no other, a philanthropist and businessman who could outdo us all, whether quoting Plato, playing a piano concerto with elegance and showmanship, or retelling one of the world’s naughtiest jokes in Chinese. On arriving at China Tang one Sunday evening for a late dinner, my husband Ceawlin and I happened upon David, who invited us to join his table, full of familiar faces. A few moments later, Tom Jones stood up and serenaded us all with his rendition of “Kiss”, to the delight of everyone.

David was a maker of magic, literally and figuratively. I remember an afternoon at his and his wife Lucy’s idyllic coastal country house in Sai Kung, Hong Kong, and no matter how hard David tried, one of his old classic card tricks kept failing to work. This enraged him beyond belief, but made the day even more entertaining.

Edward Tang, David’s son, and I met on our first day at UCL, and stuck together for our three-year History of Art course. We have remained firm friends ever since. Ed is godfather to our son John, and I have always adored him, but never have I been prouder of him or loved him more than I do now. This after all is not only a tribute to David, but also to his wonderful family, who have doted on him, held his hand and comforted him up to his last breath. Lucy has been his rock, and was the blood in his veins. Stoical to the last, she has faithfully supported David and calmly kept on top of everything, whilst navigating an emotional rollercoaster too terrible to imagine. The support, too, of David’s beloved and talented daughter Victoria has been unparalleled, with her husband Chris and beautiful baby Rocco alongside, providing the tenderness and companionship any of us would wish for during our last moments in this life.

LikeComment
376 likes

The light that shone from David inspired us all, and can never be extinguished. I can think of no one else who has brought such immeasurable joy to so many of our lives, with the driving force of a Superman and the energy of 50. Even when his health began to fade, his mind remained robust to the very last. The China Exchange, an ideas space that David founded as a “dynamic centre of excellence in Chinatown”, will continue to host varied and thought-provoking events, just as he intended. At his farewell party, the many embraces of his cherished friends will be the lasting symbol of the adoration and admiration we feel for him – an irreplaceable soul. We will celebrate him, treasure our precious memories of him and keep him with us in our hearts forever.

To see the original of this article CLICK HERE
.
Regards,
     Greg_L-W
Greg Lance-Watkins
.
 Please Be Sure To
& Link to my My Blogs
To Spread The Facts World Wide To Give Others HOPE
I Have Been Fighting Cancer since 1997 & I’M STILL HERE!
I Have Cancer, Cancer Does NOT Have Me
I just want to say sorry for copping out at times and leaving my wife Lee and friends to cope!
Any help and support YOU can give her will be hugely welcome.
I do make a lousy patient!

.

If YOU want to follow my fight against Cancer from when it started and I first presented with symptoms in 1998 see The TAB at the Header of this Blog. called >DIARY of Cancer ….ARCHIVEMEDICAL LINKSCANCER LINKSHOT LINKS< in the Sidebar.
.
YOU are welcome to call me, minded that I am NOT medically trained, if you believe I can help you in ANY way. .

Regards,
Greg_L-W.

~~~~~~~~~~#########~~~~~~~~~~
.
Posted by: Greg Lance-Watkins
tel: 44 (0)1594 – 528 337
Calls from ‘Number Withheld’ phones Are Blocked

All unanswered messages are recorded.
Leave your name & a UK land line number & I will return your call.

‘e’Mail Address: Greg_L-W@BTconnect.com

Skype: GregL-W

TWITTER: @Greg_LW

DO MAKE USE of LINKS,
>SEARCH<
&
>Side Bars<
&
The Top Bar >PAGES<
I try to make every effort to NOT infringe copyrights in any commercial way & make all corrections of fact brought to my attention by an identifiable individual
.

Please Be Sure To
.Follow Greg_LW on Twitter.

Re-TWEET my Twitterings
https://twitter.com/Greg_LW

& Publicise

My MainWebSite & Blogs

To Spread The Facts World Wide


eMail:
Greg_L-W@BTconnect.com

The BLOG:
https://InfoWebSiteUK.wordpress.com

The Main Web Site:
www.InfoWebSite.UK

~~~~~~~~~~#########~~~~~~~~~~

Enhanced by Zemanta

#Canakinumab Is Clearly The New Wonder Drug For Patients With #Heart_Attacks …

DO MAKE USE of LINKS,
>SEARCH<
&
>Side Bars<
&
The Top Bar >PAGES<

~~~~~~~~~~#########~~~~~~~~~~

.

#Canakinumab Is Clearly The New Wonder Drug For Patients With #Heart_Attacks …

.
~~~~~~~~~~#########~~~~~~~~~~

Posted by:
Greg Lance – Watkins
Greg_L-W

eMail:
Greg_L-W@BTconnect.com

The BLOG:
https://InfoWebSiteUK.wordpress.com

The Main Web Site:
www.InfoWebSite.UK

~~~~~~~~~~#########~~~~~~~~~~

 .

Hi,

Best heart drug since statins: New injection could save thousands of lives by preventing heart attacks and also slash cancer risk

  • Landmark four-year trial found Canakinumab  cut heart attack risk by 24 per cent
  • The study also suggested it could halve the risk of dying from lung cancer
  • Scientists have hailed the find and said treatment could save thousands of lives 
A breakthrough drug could prevent thousands of heart attacks (stock picture)

A breakthrough drug could prevent thousands of heart attacks (stock picture)

Thousands of lives could be saved thanks to a new heart drug hailed as the biggest breakthrough since statins.

In a landmark four-year trial, scientists found that the drug – given by injection every three months – cut the risk of heart attacks by a quarter.

The 10,000-patient study, involving 1,000 doctors in 39 countries, also suggested it could halve the risk of dying from lung cancer and prevent arthritis and gout.

Scientists last night said the treatment marked ‘a new era of therapeutics’ that could save thousands of lives.

The drug, Canakinumab, works by reducing inflammation – a major new approach in heart medicine.

For the past 30 years cholesterol-busting statins have been given to nearly all people deemed to be at risk of cardiovascular disease in a bid to save them from heart attacks and strokes. Yet half of the 200,000 people who have a heart attack in Britain each year do not have high cholesterol, meaning there is a desperate need for a different approach to treatment.

Experts have long thought that inflammation – the body’s natural responses to infection or injury – might also play a major role in causing heart attacks and strokes, possibly because it causes the condition to flare in the arteries, increasing the risk of a blockage.

In a landmark four-year trial, scientists found that the drug - given by injection every three months – cut the risk of heart attacks by 24 per cent (stock picture)

 

In a landmark four-year trial, scientists found that the drug – given by injection every three months – cut the risk of heart attacks by 24 per cent (stock picture)

The new trial, however, is the first definitive proof that cutting inflammation slashes heart risk.

Study leader Professor Paul Ridker of Harvard Medical School said the new drug opened up a ‘third front’ in the war on heart disease, following the previous focus on cholesterol and lifestyle.

Presenting his findings at the European Society of Cardiology congress in Barcelona yesterday, Prof Ridker said: ‘These findings represent the end game of more than two decades of research, stemming from a critical observation – half of heart attacks occur in people who do not have high cholesterol.

‘For the first time, we’ve been able to definitively show that lowering inflammation independent of cholesterol reduces cardiovascular risk.’

Prof Ridker, whose results are published in the New England Journal of Medicine, added: ‘This has far-reaching implications.

Ease back on salt 

Eating too much salt more than doubles the risk of heart failure, scientists have found.

Experts have long known that salt increases high-blood pressure – but the new research suggests it also does direct damage to the heart.

Researchers at the National Institute for Health and Welfare in Helsinki tracked 4,630 healthy adults for 12 years.

They found 20 per cent of people were eating more than 13.7g daily. The UK guideline is 6g.

These people were twice as likely to suffer heart failure than those who ate less than 6.8g. Lead researcher Professor Pekka Jousilahti said: ‘The heart does not like salt. High salt intake markedly increases the risk of heart failure.’

 

‘It tells us that by leveraging an entirely new way to treat patients – targeting inflammation – we may be able to significantly improve outcomes for certain very high-risk populations.’

Canakinumab is an antibody that attacks an immune-system protein called interleukin-1, which in high levels results in increased inflammation throughout the body.

The trial involved high-risk patients who had already suffered a heart attack – a group in desperate need of help because a quarter of patients suffer a second attack within five years, even with statins.

All patients in the trial took statins as well, but the research team found the addition of Canakinumab cut the risk of repeat heart attacks by 24 per cent, over and above the impact of the cholesterol drug.

People who took the drug were also 36 per cent less likely to be hospitalised with unstable angina, and 32 per cent less likely to require expensive interventional procedures such as bypass surgery.

Researchers reported a sharp rise in infections – a side effect linked to the fact inflammation protects against infection – which killed one in every 1,000 patients.

But they also found patients had a 51 per cent reduced risk of lung cancer deaths – a finding they said was ‘very exciting’ and needed further trials. Gout and arthritis, which are linked to inflammation, also fell.

Drugs giant Novartis, which makes Canakinumab, said it would immediately apply for a medical licence to use the drug for heart disease.

All patients in the trial took statins as well, but the research team found the addition of Canakinumab cut the risk of repeat heart attacks by 24 per centAll patients in the trial took statins as well, but the research team found the addition of Canakinumab cut the risk of repeat heart attacks by 24 per cent

Canakinumab is used for inflammatory problems, including rare forms of arthritis, at the cost of £9,928 per jab. It is expensive because the conditions are rare, so sales are low. Experts said the price – £40,000 a year for heart patients – would have to come down if it were to be made available on the NHS.

Professor Jeremy Pearson, of the British Heart Foundation, said: ‘These exciting and long-awaited trial results finally confirm that ongoing inflammation contributes to risk of heart disease, and could help save lives.’

American cardiologist Steven Nissen said: ‘This is as big as anything we’ve seen in a while. It’s a gateway to a very wide variety of therapies that are going to be developed.’

To see the original of this article CLICK HERE
.
Regards,
     Greg_L-W
Greg Lance-Watkins
.
 Please Be Sure To
& Link to my My Blogs
To Spread The Facts World Wide To Give Others HOPE
I Have Been Fighting Cancer since 1997 & I’M STILL HERE!
I Have Cancer, Cancer Does NOT Have Me
I just want to say sorry for copping out at times and leaving my wife Lee and friends to cope!
Any help and support YOU can give her will be hugely welcome.
I do make a lousy patient!

.

If YOU want to follow my fight against Cancer from when it started and I first presented with symptoms in 1998 see The TAB at the Header of this Blog. called >DIARY of Cancer ….ARCHIVEMEDICAL LINKSCANCER LINKSHOT LINKS< in the Sidebar.
.
YOU are welcome to call me, minded that I am NOT medically trained, if you believe I can help you in ANY way. .

Regards,
Greg_L-W.

~~~~~~~~~~#########~~~~~~~~~~
.
Posted by: Greg Lance-Watkins
tel: 44 (0)1594 – 528 337
Calls from ‘Number Withheld’ phones Are Blocked

All unanswered messages are recorded.
Leave your name & a UK land line number & I will return your call.

‘e’Mail Address: Greg_L-W@BTconnect.com

Skype: GregL-W

TWITTER: @Greg_LW

DO MAKE USE of LINKS,
>SEARCH<
&
>Side Bars<
&
The Top Bar >PAGES<
I try to make every effort to NOT infringe copyrights in any commercial way & make all corrections of fact brought to my attention by an identifiable individual
.

Please Be Sure To
.Follow Greg_LW on Twitter.

Re-TWEET my Twitterings
https://twitter.com/Greg_LW

& Publicise

My MainWebSite & Blogs

To Spread The Facts World Wide


eMail:
Greg_L-W@BTconnect.com

The BLOG:
https://InfoWebSiteUK.wordpress.com

The Main Web Site:
www.InfoWebSite.UK

~~~~~~~~~~#########~~~~~~~~~~

Enhanced by Zemanta

Heart attack and cancer deaths could be cut by a new drug …

DO MAKE USE of LINKS,
>SEARCH<
&
>Side Bars<
&
The Top Bar >PAGES<

~~~~~~~~~~#########~~~~~~~~~~

.

Heart attack and cancer deaths could be cut by a new drug …

.
~~~~~~~~~~#########~~~~~~~~~~

Posted by:
Greg Lance – Watkins
Greg_L-W

eMail:
Greg_L-W@BTconnect.com

The BLOG:
https://InfoWebSiteUK.wordpress.com

The Main Web Site:
www.InfoWebSite.UK

~~~~~~~~~~#########~~~~~~~~~~

 .

Hi,

Heart attack and cancer deaths could be cut by new drug

A study on an anti-inflammatory shows a 15% reduction in heart attack risk and the number of cancer deaths cut by half.

Stock photo ID:627196908
Upload date:January 04, 2017
Image: Results of the trial have been described as ‘very exciting’

A new drug that could help reduce the risk of heart attacks and cut cancer deaths has been hailed as an “exciting” breakthrough.

Canakinumab, an anti-inflammatory, was used in a trial involving more than 10,000 patients, all of whom have had a heart attack but had not been diagnosed with cancer.

 

They were treated with the drug, which is given by injection, once every three months and monitored for up to four years.

The study showed a 15% reduction in the risk of heart attacks and strokes and the number of cancer deaths cut by half.

One of the researchers, Dr Paul Ridker of Brigham and Women’s Hospital in Boston, said the findings have “far-reaching implications”.

He said: “For the first time, we’ve been able to definitively show that lowering inflammation independent of cholesterol reduces cardiovascular risk.

“It tells us that by leveraging an entirely new way to treat patients – targeting inflammation – we may be able to significantly improve outcomes for certain very high-risk populations.”

The benefits seen in the patients were “above and beyond” those seen in patients who just took statins, the hospital said.

Dr Ridker said: “In my lifetime, I’ve gotten to see three broad eras of preventative cardiology.

“In the first, we recognised the importance of diet, exercise and smoking cessation. In the second, we saw the tremendous value of lipid-lowering drugs such as statins. Now, we’re cracking the door open on the third era.

“This is very exciting.”

Regarding the cancer findings, Dr Ridker said more research was needed but there was the “possibility of slowing the progression of certain cancers”.

Gary Gibbons, director of the National Heart, Lung, and Blood Institute, said: “Although this trial provides compelling evidence that targeting inflammation has efficacy in preventing recurrent cardiovascular events, we look forward to findings from additional trials, such as the NHLBI-funded Cardiovascular Inflammation Reduction Trial, to further refine the best therapeutic strategies for preventing cardiovascular disease.”

To see the original of this article CLICK HERE
.
Regards,
     Greg_L-W
Greg Lance-Watkins
.
 Please Be Sure To
& Link to my My Blogs
To Spread The Facts World Wide To Give Others HOPE
I Have Been Fighting Cancer since 1997 & I’M STILL HERE!
I Have Cancer, Cancer Does NOT Have Me
I just want to say sorry for copping out at times and leaving my wife Lee and friends to cope!
Any help and support YOU can give her will be hugely welcome.
I do make a lousy patient!

.

If YOU want to follow my fight against Cancer from when it started and I first presented with symptoms in 1998 see The TAB at the Header of this Blog. called >DIARY of Cancer ….ARCHIVEMEDICAL LINKSCANCER LINKSHOT LINKS< in the Sidebar.
.
YOU are welcome to call me, minded that I am NOT medically trained, if you believe I can help you in ANY way. .

Regards,
Greg_L-W.

~~~~~~~~~~#########~~~~~~~~~~
.
Posted by: Greg Lance-Watkins
tel: 44 (0)1594 – 528 337
Calls from ‘Number Withheld’ phones Are Blocked

All unanswered messages are recorded.
Leave your name & a UK land line number & I will return your call.

‘e’Mail Address: Greg_L-W@BTconnect.com

Skype: GregL-W

TWITTER: @Greg_LW

DO MAKE USE of LINKS,
>SEARCH<
&
>Side Bars<
&
The Top Bar >PAGES<
I try to make every effort to NOT infringe copyrights in any commercial way & make all corrections of fact brought to my attention by an identifiable individual
.

Please Be Sure To
.Follow Greg_LW on Twitter.

Re-TWEET my Twitterings
https://twitter.com/Greg_LW

& Publicise

My MainWebSite & Blogs

To Spread The Facts World Wide


eMail:
Greg_L-W@BTconnect.com

The BLOG:
https://InfoWebSiteUK.wordpress.com

The Main Web Site:
www.InfoWebSite.UK

~~~~~~~~~~#########~~~~~~~~~~

Enhanced by Zemanta

#Canakinumab #Novartis study shows drug may halve cancer deaths and cut heart attack risks …

DO MAKE USE of LINKS,
>SEARCH<
&
>Side Bars<
&
The Top Bar >PAGES<

~~~~~~~~~~#########~~~~~~~~~~

.

#Canakinumab #Novartis study shows drug may halve cancer deaths and cut heart attack risks …

.
~~~~~~~~~~#########~~~~~~~~~~

Posted by:
Greg Lance – Watkins
Greg_L-W

eMail:
Greg_L-W@BTconnect.com

The BLOG:
https://InfoWebSiteUK.wordpress.com

The Main Web Site:
www.InfoWebSite.UK

~~~~~~~~~~#########~~~~~~~~~~

 .

Hi,

`Milestone´ study shows drug may halve cancer deaths and cut heart attack risks

An “exciting” new study has revealed a drug that could help reduce the risk of heart attacks and cut cancer deaths.

More than 10,000 patients took part in a trial using the anti-inflammatory Canakinumab, the results of which were presented at the European Society of Cardiology meeting in Barcelona, Spain.

The patients, all of whom had previously had a heart attack but had not been diagnosed with cancer, were treated with the drug once every three months, and monitored for up to four years.

The Canakinumab Anti-inflammatory Thrombosis Outcomes study, or CANTOS, showed a 15% reduction in the risk of heart attacks and strokes, and cancer deaths cut in half, the hospital where one of the lead authors is based said.

John Stilwell
 

John Stilwell

Dr Paul Ridker of Brigham and Women’s Hospital in Boston, said the study “represents a milestone in a long journey”, adding that the findings “usher in a new era of therapeutics”.

He said: “For the first time, we’ve been able to definitively show that lowering inflammation independent of cholesterol reduces cardiovascular risk.

“This has far-reaching implications. It tells us that by leveraging an entirely new way to treat patients – targeting inflammation – we may be able to significantly improve outcomes for certain very high-risk populations.”

The hospital said the reductions in risk were “above and beyond” those seen in patients who only took statins.

Statins
 

Statins

Dr Ridker said the study showed another way to prevent repeated heart attacks, through the use of anti-inflammatories.

He said: “In my lifetime, I’ve gotten to see three broad eras of preventative cardiology.

“In the first, we recognised the importance of diet, exercise and smoking cessation. In the second, we saw the tremendous value of lipid-lowering drugs such as statins. Now, we’re cracking the door open on the third era. This is very exciting.”

Gary Gibbons, director of the National Heart, Lung, and Blood Institute, said the results provided a platform on which to carry out further trials and research.

Stopping smoking, attending to diet and cutting down on alcohol are still the best primary steps to take (Jonathan Brady/PA)
 

Stopping smoking, attending to diet and cutting down on alcohol are still the best primary steps to take (Jonathan Brady/PA)

He said: “Although this trial provides compelling evidence that targeting inflammation has efficacy in preventing recurrent cardiovascular events, we look forward to findings from additional trials, such as the NHLBI-funded Cardiovascular Inflammation Reduction Trial, to further refine the best therapeutic strategies for preventing cardiovascular disease.”

In looking at the effects of the drug on cancer, Dr Ridker said the findings indicate “the possibility of slowing the progression of certain cancers” but said further research is required.

The study was funded by Novartis Pharmaceuticals.

To see the original of this article CLICK HERE
.
Regards,
     Greg_L-W
Greg Lance-Watkins
.
 Please Be Sure To
& Link to my My Blogs
To Spread The Facts World Wide To Give Others HOPE
I Have Been Fighting Cancer since 1997 & I’M STILL HERE!
I Have Cancer, Cancer Does NOT Have Me
I just want to say sorry for copping out at times and leaving my wife Lee and friends to cope!
Any help and support YOU can give her will be hugely welcome.
I do make a lousy patient!

.

If YOU want to follow my fight against Cancer from when it started and I first presented with symptoms in 1998 see The TAB at the Header of this Blog. called >DIARY of Cancer ….ARCHIVEMEDICAL LINKSCANCER LINKSHOT LINKS< in the Sidebar.
.
YOU are welcome to call me, minded that I am NOT medically trained, if you believe I can help you in ANY way. .

Regards,
Greg_L-W.

~~~~~~~~~~#########~~~~~~~~~~
.
Posted by: Greg Lance-Watkins
tel: 44 (0)1594 – 528 337
Calls from ‘Number Withheld’ phones Are Blocked

All unanswered messages are recorded.
Leave your name & a UK land line number & I will return your call.

‘e’Mail Address: Greg_L-W@BTconnect.com

Skype: GregL-W

TWITTER: @Greg_LW

DO MAKE USE of LINKS,
>SEARCH<
&
>Side Bars<
&
The Top Bar >PAGES<
I try to make every effort to NOT infringe copyrights in any commercial way & make all corrections of fact brought to my attention by an identifiable individual
.

Please Be Sure To
.Follow Greg_LW on Twitter.

Re-TWEET my Twitterings
https://twitter.com/Greg_LW

& Publicise

My MainWebSite & Blogs

To Spread The Facts World Wide


eMail:
Greg_L-W@BTconnect.com

The BLOG:
https://InfoWebSiteUK.wordpress.com

The Main Web Site:
www.InfoWebSite.UK

~~~~~~~~~~#########~~~~~~~~~~

Enhanced by Zemanta