#Canakinumab Is Clearly The New Wonder Drug For Patients With #Heart_Attacks …

DO MAKE USE of LINKS,
>SEARCH<
&
>Side Bars<
&
The Top Bar >PAGES<

~~~~~~~~~~#########~~~~~~~~~~

.

#Canakinumab Is Clearly The New Wonder Drug For Patients With #Heart_Attacks …

.
~~~~~~~~~~#########~~~~~~~~~~

Posted by:
Greg Lance – Watkins
Greg_L-W

eMail:
Greg_L-W@BTconnect.com

The BLOG:
https://InfoWebSiteUK.wordpress.com

The Main Web Site:
www.InfoWebSite.UK

~~~~~~~~~~#########~~~~~~~~~~

 .

Hi,

Best heart drug since statins: New injection could save thousands of lives by preventing heart attacks and also slash cancer risk

  • Landmark four-year trial found Canakinumab  cut heart attack risk by 24 per cent
  • The study also suggested it could halve the risk of dying from lung cancer
  • Scientists have hailed the find and said treatment could save thousands of lives 
A breakthrough drug could prevent thousands of heart attacks (stock picture)

A breakthrough drug could prevent thousands of heart attacks (stock picture)

Thousands of lives could be saved thanks to a new heart drug hailed as the biggest breakthrough since statins.

In a landmark four-year trial, scientists found that the drug – given by injection every three months – cut the risk of heart attacks by a quarter.

The 10,000-patient study, involving 1,000 doctors in 39 countries, also suggested it could halve the risk of dying from lung cancer and prevent arthritis and gout.

Scientists last night said the treatment marked ‘a new era of therapeutics’ that could save thousands of lives.

The drug, Canakinumab, works by reducing inflammation – a major new approach in heart medicine.

For the past 30 years cholesterol-busting statins have been given to nearly all people deemed to be at risk of cardiovascular disease in a bid to save them from heart attacks and strokes. Yet half of the 200,000 people who have a heart attack in Britain each year do not have high cholesterol, meaning there is a desperate need for a different approach to treatment.

Experts have long thought that inflammation – the body’s natural responses to infection or injury – might also play a major role in causing heart attacks and strokes, possibly because it causes the condition to flare in the arteries, increasing the risk of a blockage.

In a landmark four-year trial, scientists found that the drug - given by injection every three months – cut the risk of heart attacks by 24 per cent (stock picture)

 

In a landmark four-year trial, scientists found that the drug – given by injection every three months – cut the risk of heart attacks by 24 per cent (stock picture)

The new trial, however, is the first definitive proof that cutting inflammation slashes heart risk.

Study leader Professor Paul Ridker of Harvard Medical School said the new drug opened up a ‘third front’ in the war on heart disease, following the previous focus on cholesterol and lifestyle.

Presenting his findings at the European Society of Cardiology congress in Barcelona yesterday, Prof Ridker said: ‘These findings represent the end game of more than two decades of research, stemming from a critical observation – half of heart attacks occur in people who do not have high cholesterol.

‘For the first time, we’ve been able to definitively show that lowering inflammation independent of cholesterol reduces cardiovascular risk.’

Prof Ridker, whose results are published in the New England Journal of Medicine, added: ‘This has far-reaching implications.

Ease back on salt 

Eating too much salt more than doubles the risk of heart failure, scientists have found.

Experts have long known that salt increases high-blood pressure – but the new research suggests it also does direct damage to the heart.

Researchers at the National Institute for Health and Welfare in Helsinki tracked 4,630 healthy adults for 12 years.

They found 20 per cent of people were eating more than 13.7g daily. The UK guideline is 6g.

These people were twice as likely to suffer heart failure than those who ate less than 6.8g. Lead researcher Professor Pekka Jousilahti said: ‘The heart does not like salt. High salt intake markedly increases the risk of heart failure.’

 

‘It tells us that by leveraging an entirely new way to treat patients – targeting inflammation – we may be able to significantly improve outcomes for certain very high-risk populations.’

Canakinumab is an antibody that attacks an immune-system protein called interleukin-1, which in high levels results in increased inflammation throughout the body.

The trial involved high-risk patients who had already suffered a heart attack – a group in desperate need of help because a quarter of patients suffer a second attack within five years, even with statins.

All patients in the trial took statins as well, but the research team found the addition of Canakinumab cut the risk of repeat heart attacks by 24 per cent, over and above the impact of the cholesterol drug.

People who took the drug were also 36 per cent less likely to be hospitalised with unstable angina, and 32 per cent less likely to require expensive interventional procedures such as bypass surgery.

Researchers reported a sharp rise in infections – a side effect linked to the fact inflammation protects against infection – which killed one in every 1,000 patients.

But they also found patients had a 51 per cent reduced risk of lung cancer deaths – a finding they said was ‘very exciting’ and needed further trials. Gout and arthritis, which are linked to inflammation, also fell.

Drugs giant Novartis, which makes Canakinumab, said it would immediately apply for a medical licence to use the drug for heart disease.

All patients in the trial took statins as well, but the research team found the addition of Canakinumab cut the risk of repeat heart attacks by 24 per centAll patients in the trial took statins as well, but the research team found the addition of Canakinumab cut the risk of repeat heart attacks by 24 per cent

Canakinumab is used for inflammatory problems, including rare forms of arthritis, at the cost of £9,928 per jab. It is expensive because the conditions are rare, so sales are low. Experts said the price – £40,000 a year for heart patients – would have to come down if it were to be made available on the NHS.

Professor Jeremy Pearson, of the British Heart Foundation, said: ‘These exciting and long-awaited trial results finally confirm that ongoing inflammation contributes to risk of heart disease, and could help save lives.’

American cardiologist Steven Nissen said: ‘This is as big as anything we’ve seen in a while. It’s a gateway to a very wide variety of therapies that are going to be developed.’

To see the original of this article CLICK HERE
.
Regards,
     Greg_L-W
Greg Lance-Watkins
.
 Please Be Sure To
& Link to my My Blogs
To Spread The Facts World Wide To Give Others HOPE
I Have Been Fighting Cancer since 1997 & I’M STILL HERE!
I Have Cancer, Cancer Does NOT Have Me
I just want to say sorry for copping out at times and leaving my wife Lee and friends to cope!
Any help and support YOU can give her will be hugely welcome.
I do make a lousy patient!

.

If YOU want to follow my fight against Cancer from when it started and I first presented with symptoms in 1998 see The TAB at the Header of this Blog. called >DIARY of Cancer ….ARCHIVEMEDICAL LINKSCANCER LINKSHOT LINKS< in the Sidebar.
.
YOU are welcome to call me, minded that I am NOT medically trained, if you believe I can help you in ANY way. .

Regards,
Greg_L-W.

~~~~~~~~~~#########~~~~~~~~~~
.
Posted by: Greg Lance-Watkins
tel: 44 (0)1594 – 528 337
Calls from ‘Number Withheld’ phones Are Blocked

All unanswered messages are recorded.
Leave your name & a UK land line number & I will return your call.

‘e’Mail Address: Greg_L-W@BTconnect.com

Skype: GregL-W

TWITTER: @Greg_LW

DO MAKE USE of LINKS,
>SEARCH<
&
>Side Bars<
&
The Top Bar >PAGES<
I try to make every effort to NOT infringe copyrights in any commercial way & make all corrections of fact brought to my attention by an identifiable individual
.

Please Be Sure To
.Follow Greg_LW on Twitter.

Re-TWEET my Twitterings
https://twitter.com/Greg_LW

& Publicise

My MainWebSite & Blogs

To Spread The Facts World Wide


eMail:
Greg_L-W@BTconnect.com

The BLOG:
https://InfoWebSiteUK.wordpress.com

The Main Web Site:
www.InfoWebSite.UK

~~~~~~~~~~#########~~~~~~~~~~

Enhanced by Zemanta
Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s