Cancer Can Be Traced To Pre Human Fossilised Hominids

Cancer Can Be Traced To Pre Human Fossilised Hominids
.

~~~~~~~~~~#########~~~~~~~~~~

Posted by:
Greg Lance – Watkins
Greg_L-W

eMail: Greg_L-W@BTconnect.com

~~~~~~~~~~#########~~~~~~~~~~

Hi,

Earliest Human Cancer Found in 1.7-Million-Year-Old Bone

The ancient toe from a human relative in South Africa could have important implications for modern medical research.

CANCER IN EARLY HOMINID 01 TOE BONEEvidence of Cancer in an early hominid
A MicroCT image of a Tumor in a toe bone

In the fossil-rich region of South Africa known as the Cradle of Humankind, scientists have discovered the earliest known case of one of the world’s most deadly diseases.

Using 3-D imaging, the researchers have diagnosed an aggressive type of cancer called osteosarcoma in a foot bone belonging to a human relative who died in Swartkrans Cave between 1.6 and 1.8 million years ago.

 

The discovery—which has just been published in the South African Journal of Science—suggests that, while modern lifestyles have increased the incidences of cancer, especially in industrialized countries, the triggers for the disease are embedded deep within the human evolutionary past.

“You can opt for the paleo diet, you can have as clean a living environment as you want, but the capacity for these diseases is ancient, and it’s within us regardless of what you do to yourselves,” says study co-author Edward Odes of the University of the Witwatersrand.

The Phantom Menace

The precise origins of cancer have been a source of debate due, in part, to the scarcity of historical evidence. Possibly the earliest reference to the disease is attributed to the great Egyptian physician Imhotep, who lived around 2600 B.C. In his writings, Imhotep describes an affliction characterized by a “bulging mass in the breast” that was resistant to any known therapies.

But most ancient texts had little to offer on the malady, and anatomically accurate descriptions of malignant tumors didn’t appear until the late 18th century.

The likely reason that cancer is a relative newcomer in the historical record is that it most commonly afflicts those 65 and older, and for a long time, few people lived long enough for cancer to become a concern.

“Civilization did not cause cancer,” writes oncologist Siddhartha Mukherjee in his book, The Emperor of All Maladies, “but by extending human life spans, civilization unveiled it.”

Evidence for cancer has also been elusive in the fossil record, which preserves only a miniscule fraction of the bones of individuals who lived at any given time. Some researchers have sought answers in mummified bodies, where they could study preserved soft tissue.

In 1990, for instance, autopsies performed on thousand-year-old mummies in Peru revealed at least one case of a woman in her mid-30s with a malignant tumor in her upper-left arm. The mass had grown so large that it likely burst through her skin while she was still alive.

Hard Evidence

The practice of mummification only goes back a few thousand years, while the fossil record goes back millions. Now, Odes and his colleagues are highly confident that the hominin bone found at the Swartkrans site near Johannesburg holds the oldest known case of malignant cancer.

 

CANCER IN EARLY HOMINID 02 TOE BONEA Different Image
of the same bone

Using a method called micro-CT imaging, the research team studied detailed 2-D and 3-D images of the fossil’s interior. Images recorded the density differences within the bone and generated views of the fragment from all directions.

The abnormal growth pattern of bone tissue—including a distinctive, cauliflower-like external appearance—led the team to diagnose the condition as osteosarcoma, which today afflicts mostly children and young adults.

“We compared the images,” says Odes, referring to the fossil and a modern biopsy specimen. “It was bingo.”

The fossil, a fragment of a toe bone from the left foot, is the only part of the skeleton that was found. It preserved too little information to determine which hominin species it belonged to, whether it was an adult or a child, or even if the cancer was the ultimate cause of death.

One thing the scientists do know: It would have been extremely painful, affecting the individual’s ability to walk or run.

A Moving Target

In addition to the toe with the malignant growth, the team analyzed another, even older fossil with a tumor, albeit a benign one.

In another study in the same journal, the team describes a growth in a vertebrae from a 1.98-million-year-old juvenile skeleton of Australopithecus sediba, discovered by National Geographic Explorer-in-Residence Lee Berger at a site called Malapa, a few miles from Swartkrans. Prior to this discovery, the oldest known benign growth was in the 120,000-year-old rib of a Neanderthal, excavated in Croatia.

The scientists see the benign tumor found at Malapa as further supporting evidence for the existence of malignant cancer among our early relations.

“A tumor is new growth of bone or tissue, where you have a sliding scale from benign to malignant,” says paleoanthropologist Patrick S. Randolph-Quinney, one of the investigating scientists.

“On the benign side, there are mechanisms that keep these tumors in check, so they are self-limiting, or they reach a certain size and they basically stay there. Whereas cancer is the extension of that growth process without the control mechanisms.”

The team also sees their findings as an important reminder that cancer is a moving target. Our ancient lineage endowed us with genes that contain the capacity for cancer, but the disease manifests itself in myriad ways when we are exposed to changes in our environment.

For instance, stomach cancer was more prevalent until the late 19th century, possibly because of carcinogens that had been in food preservatives. Today, colon cancer is on the rise, likely because of diets high in saturated fats.

“The modern external environment is doing things to our historical internal environment that we’ve never encountered before in our evolutionary history,” says Odes.

 

To view the original CLICK HERE

Regards,
Greg_L-W.

~~~~~~~~~~#########~~~~~~~~~~
Posted by: Greg Lance-Watkins
tel: 44 (0)1594 – 528 337
Calls from ‘Number Withheld’ phones Are Blocked

All unanswered messages are recorded.
Leave your name & a UK land line number & I will return your call.

‘e’Mail Address: Greg_L-W@BTconnect.com

Accuracy & Copyright Statement: CLICK HERE

Summary, archive, facts & comments on UKIP: http://UKIP-vs-EUkip.com
DO MAKE USE of LINKS,
>SEARCH<
&
>Side Bars<
&
The Top Bar >PAGES<Also:

Details & Links: http://GregLanceWatkins.com

UKIP Its ASSOCIATES & DETAILS: CLICK HERE
Views I respect & almost Totally Share: CLICK HERE
General ‘Stuff’: http://GL-W.com
http://Leave-The-EU.com
Documents, Essays & Treaties: https://GLWdocuments.wordpress.com/
The Hamlet of Stroat: http://Stroat-Gloucestershire.com
The Study of a Wind Turbine Application: CLICK HERE
Health Blog.: http://GregLW.com
Chepstow Chat: http://ChepstowChat.wordpress.com/
Christopher Storey: http://ChristopherStory.wordpress.com/
Des Watkins DFC: http://DesWatkins.wordpress.com/
Hollie Greig etc.: http://HollieGreigetc.wordpress.com/
Psycheocracy: http://Psycheocracy.wordpress.com/
The McCann Case: http://TheMcCannCase.wordpress.com/
The Speculative Society of Edinburgh: http://SSOE.wordpress.com/
Stolen Kids, Dunblane: http://StolenKids-Dunblane.blogspot.com/
Stolen Kids, Bloggers: http://stolenkids-bloggers.blogspot.co.uk/

Skype: GregL-W

TWITTER: @Greg_LW

Stolen Kids Blogs with links:
http://StolenKids-Bloggers.Blogspot.com
Stolen Oyster with links:
http://StolenOyster-Bloggers.Blogspot.com
Stolen Trust with links:
http://StolenTrust-Bloggers.Blogspot.com
Stolen Childhood with links:
http://StolenChildhood-Bloggers.Blogspot.com
NB:
  • I NEVER post anonymously on the internet
  • ALL MY BLOGS & WEB SITES are clearly sourced to me
  • I do NOT use an obfuscated eMail address to hide behind
  • I do NOT use or bother reading FaceBook
  • I DO have a Voice Mail Message System
  • I ONLY GUARANTEE to answer identifiable eMails
  • I ONLY GUARANTEE to phone back identifiable UK Land Line Messages
  • I do NOT accept phone calls from witheld numbers
  • I Regret due to BT in this area I have a rubbish Broadband connection
  • I AM opposed to British membership of The EU
  • I AM opposed to Welsh, Scottish or English Independence within an interdependent UK
  • I am NOT a WARMIST
  • I do NOT believe the IPCC Climate Propaganda re Anthropogenic Global Warming
  • I AM strongly opposed to the subsidy or use of failed technologies eg. WIND TURBINES
  • I AM IN FAVOUR of rapid research & development of NEW NUCLEAR technologies
  • I see no evidence to trust POLITICIANS at any level or of any persuasion
  • I do NOT believe in GODS singular or plural, Bronze Age or Modern
  • I value the NHS as a HEALTH SERVICE NOT a Lifestyle support
  • I believe in a DEATH PENALTY for serial or GBH rape.
  • I believe in a DEATH PENALTY for serial, terrorist, mass or for pleasure murder.
  • I believe in a DEATH PENALTY for serial gross child abuse including sexual.
  • I do NOT trust or believe in armed police
  • I believe in EUTHENASIA under clearly defined & legal terms

Please Be Sure To
.Follow Greg_LW on Twitter.

Re-TWEET my Twitterings

& Publicise My Blogs
To Spread The Facts World Wide
~~~~~~~~~~#########~~~~~~~~~~
 

 INDEPENDENT Leave-the-EU Alliance

Reclaim YOUR Future 
&
GET YOUR COUNTRY BACK
Deny the self serving political clique ANY Democratic claims to legitimacy
Write Upon Your Ballot Paper at EVERY election:
.
to Reclaim YOUR Future 
&
GET YOUR COUNTRY BACK

 Please Be Sure To .Follow Greg_LW on Twitter. Re-TWEET my Twitterings

& Publicise My Blogs 
To Spread The Facts World Wide
of
OUR-ENEMY-WITHIN

&

To Leave-The-EU
 
Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s